The Swemed CK-MB Reagent Kit 25 ml is a professional cardiac biochemistry reagent intended for measurement of CK-MB activity in serum using an immunoinhibition kinetic method.
The method measures creatine kinase activity in the presence of an antibody against the CK-M subunit. According to the Swemed product literature, this antibody inhibits CK-MM activity and half of the CK-MB activity while leaving the B-subunit activity available for measurement.
CK-MB is a cardiac-associated enzyme fraction that has historically been used in laboratory assessment of myocardial injury. Modern cardiac evaluation commonly includes additional biomarkers such as cardiac troponins, and CK-MB results should always be interpreted in the context of the complete clinical picture.
This reagent is intended for professional in vitro diagnostic use only in pathology laboratories, diagnostic centres, hospitals and clinical biochemistry laboratories.
| Product Detail | Information |
|---|---|
| Product Name | CK-MB Reagent Kit |
| Brand | Swemed Diagnostics |
| Pack Size | 25 ml |
| Product Type | Cardiac Biochemistry Reagent |
| Test Parameter | CK-MB |
| Method | Immunoinhibition |
| Measurement Type | Kinetic |
| Specimen | Serum |
| Wavelength | 340 nm |
| Reaction Temperature | 37°C |
| Reaction Slope | Increasing |
| Cuvette Path Length | 1 cm |
| Blank | Water Blank |
| Total Reagent Volume | 1000 µl |
| Sample Volume | 50 µl |
| Delay Time | 300 seconds |
| Reaction Time | 120 seconds |
| Reading Interval | 60 seconds |
| Factor | 6752 |
| Linearity | Up to 1500 U/L |
| Units | U/L |
| Seller | Microsidd India |
| Website | microsidd.com |
| Location | Bangalore / Bengaluru, Karnataka, India |
The technical assay information above is taken from Swemed Diagnostics' CK-MB product literature.
The CK-MB system consists of:
| Component | Description |
|---|---|
| Reagent R1 | Ready to Use |
| Reagent R2 | Ready to Use |
Swemed states that both reagents are supplied ready to use and remain stable until the expiry date stated on the label when stored appropriately.
The Swemed CK-MB assay uses immunoinhibition to suppress CK-M activity, allowing measurement related to the B-subunit activity of CK-MB.
The assay uses a kinetic measurement format with absorbance change monitored over time at 340 nm.
R1 and R2 are supplied ready to use, helping simplify laboratory reagent preparation.
The 25 ml configuration is useful for laboratories with routine or moderate CK-MB testing volumes. Swemed's current catalogue also lists CK-MB as a cardiac reagent using an immunoinhibition kinetic method.
The reagent can be incorporated into professional laboratory cardiac-marker workflows alongside other relevant tests, subject to laboratory protocols and current clinical practice.
The Swemed CK-MB Reagent Kit is intended for professional laboratory measurement of CK-MB activity in serum using an immunoinhibition kinetic method.
It is intended for use by trained laboratory personnel and for in vitro diagnostic use only.
The assay measures creatine kinase activity in the presence of an antibody directed against the CK-M monomer.
According to the manufacturer:
The resulting kinetic activity is measured photometrically.
Swemed instructs laboratories to prepare the working reagent by mixing:
4 parts Reagent R1 + 1 part Reagent R2
The combined working reagent is stated to remain stable for approximately 2 weeks at 2–8°C, protected from direct light.
| Test Parameter | Manufacturer Specification |
|---|---|
| Parameter | CK-MB |
| Method | Immunoinhibition |
| Mode | Kinetic |
| Wavelength | 340 nm |
| Cuvette | 1 cm path length |
| Reaction Slope | Increasing |
| Temperature | 37°C |
| Blank | Water Blank |
| Total Reagent Volume | 1000 µl |
| Sample Volume | 50 µl |
| Delay Time | 300 seconds |
| Reaction Time | 120 seconds |
| Interval Time | 60 seconds |
| Factor | 6752 |
| Linearity | 1500 U/L |
| Unit | U/L |
| Component | Macro Method | Semi-Micro Method |
|---|---|---|
| Reagent R1 + R2 | 800 + 200 µl | 400 + 100 µl |
| Sample | 50 µl | 25 µl |
After adding the sample, mix and incubate for 300 seconds at 37°C. Measure the change in absorbance every minute for 2 minutes, then calculate the mean absorbance change per minute.
The manufacturer identifies serum as the specimen of choice.
Swemed also notes that CK-MB activity decreases relatively quickly after collection, reporting approximately 10% loss of activity after 1 hour at 25°C.
Proper sample collection, handling and timely analysis are therefore important.
| Parameter | Manufacturer Reference |
|---|---|
| CK-MB | 0–24 U/L |
Each laboratory should validate reference intervals according to its own population, analyser configuration, method and laboratory policy.
CK-MB is an isoenzyme of creatine kinase that has historically been associated with cardiac muscle injury.
The Swemed insert states that CK-MB levels may rise within several hours following myocardial infarction, reach a peak later, and subsequently decline when no further myocardial injury occurs.
In current clinical practice, cardiac troponins are generally the preferred biomarkers for diagnosing acute myocardial injury, while CK-MB may still have a role in selected laboratory or clinical circumstances.
CK-MB results should never be interpreted in isolation.
| Test | Laboratory Relevance |
|---|---|
| CK-MB | Cardiac-associated creatine kinase fraction |
| Total CK / CK-NAC | Total creatine kinase activity |
| Troponin I / T | Major biomarkers of myocardial injury |
| LDH | Tissue injury-related enzyme |
| AST / SGOT | May be elevated in several tissue-injury conditions |
| Buyer Type | Typical Application |
|---|---|
| Pathology Laboratories | CK-MB and cardiac biochemistry testing |
| Diagnostic Centres | Cardiac-marker investigations |
| Hospital Laboratories | Emergency and inpatient laboratory testing |
| Cardiac Hospitals | Professional cardiac biochemistry testing |
| Medical Institutions | Diagnostic and teaching laboratories |
| Clinical Chemistry Laboratories | Routine enzyme testing |
| Healthcare Organisations | Institutional laboratory procurement |
| Laboratory Distributors | Professional supply where permitted |
Microsidd India supplies cardiac biochemistry reagents and laboratory diagnostic products from Bangalore / Bengaluru, Karnataka for professional pathology laboratories, diagnostic centres, hospitals and institutional healthcare buyers.
The Swemed CK-MB Reagent Kit 25 ml is suitable for laboratories performing professional clinical chemistry and cardiac-marker testing and can be ordered through microsidd.com, subject to stock availability and delivery serviceability.
This product is relevant for buyers searching for:
The Swemed CK-MB Reagent Kit 25 ml is a professional clinical biochemistry reagent for measuring CK-MB activity in serum using an immunoinhibition kinetic method.
It uses an immunoinhibition method with kinetic measurement.
The manufacturer identifies serum as the sample of choice.
The assay is measured at 340 nm.
The manufacturer's macro procedure uses 50 µl serum, while the semi-micro procedure uses 25 µl.
The product insert states linearity up to 1500 U/L.
Yes. Reagent R1 and Reagent R2 are supplied ready to use.
The product can be purchased from Microsidd India through microsidd.com, subject to availability.
| Entity | Details |
|---|---|
| Product | CK-MB Reagent Kit |
| Brand | Swemed Diagnostics |
| Pack Size | 25 ml |
| Method | Immunoinhibition |
| Measurement | Kinetic |
| Parameter | CK-MB |
| Specimen | Serum |
| Category | Laboratory Reagents |
| Subcategory | Biochemistry Reagents |
| Clinical Category | Cardiac Markers |
| Seller | Microsidd India |
| City | Bangalore / Bengaluru |
| State | Karnataka |
| Country | India |
| Website | microsidd.com |
| Buyer Type | B2B / Laboratory / Healthcare |
Cardiac and biochemistry reagents require careful procurement because laboratories need the correct analyte, method, reagent configuration, pack size, analyser compatibility, storage conditions, expiry and dependable seller support.
Microsidd India has been involved in the IVD and diagnostic-product sector since 2000 and specialises in diagnostic, laboratory and healthcare supplies rather than operating as a general-purpose ecommerce marketplace.
Microsidd also maintains established manufacturer and authorised brand relationships across several diagnostic categories, giving professional buyers the advantage of purchasing through an identifiable diagnostic-products specialist.
| Buying Factor | Microsidd.com | Large Online Marketplaces | Offline / Local Suppliers |
|---|---|---|---|
| Seller Specialisation | Diagnostic and laboratory focused | Seller expertise varies | Depends on dealer |
| Product Knowledge | Suitable for laboratory-product enquiries | Often general marketplace support | Dealer dependent |
| Seller Identity | Direct purchase from Microsidd India | Marketplace and actual seller may differ | Usually identifiable |
| Manufacturer Relationships | Established diagnostic manufacturer relationships across multiple categories | Seller dependent | Varies |
| Method Verification | Product parameter and methodology can be checked before ordering | Similar listings may cause confusion | Depends on stock and dealer knowledge |
| GST Invoice | Available for eligible purchases | Seller dependent | May vary |
| B2B Procurement | Suitable for laboratories and healthcare institutions | Seller dependent | Usually local |
| Product Range | Specialist laboratory and diagnostic catalogue | Broad but not specialised | Usually limited by local stock |
| Customer Support | Direct Microsidd support | Marketplace plus seller layer | Local support |
| Seller Accountability | One identifiable specialist supplier | Seller may vary by listing | Depends on supplier |
| Online Convenience | Direct ordering through microsidd.com | Convenient | May require phone or store visit |
| Geographic Reach | India-wide subject to serviceability | Broad | Usually regional |
| Microsidd Advantage | Benefit to Laboratory Buyers |
|---|---|
| Diagnostic Product Specialisation | Better suited to professional laboratory procurement |
| IVD Experience Since 2000 | Long-standing experience in diagnostic-product supply |
| Manufacturer Relationships | Established relationships across diagnostic categories |
| Direct Seller Accountability | Purchase directly from Microsidd India |
| GST Invoice | Useful for laboratories and institutional buyers |
| Product Verification Support | Method, pack and product specifications can be confirmed before ordering |
| Multi-Category Procurement | Cardiac, biochemistry, rapid-test and laboratory products available together |
| Bangalore-Based Operations | Convenient for laboratories in Bengaluru and Karnataka |
| India-Wide Supply | Delivery to serviceable locations across India |
| Direct Customer Support | Product and order queries handled directly by Microsidd |
It is intended for professional measurement of CK-MB activity in serum using an immunoinhibition kinetic method.
The listed pack size is 25 ml.
The assay uses an immunoinhibition kinetic method.
Swemed identifies serum as the sample of choice.
The assay uses 340 nm.
The assay is performed at 37°C.
The stated reagent volume is 1000 µl.
The macro procedure uses 50 µl and the semi-micro procedure uses 25 µl.
The manufacturer insert states 1500 U/L.
Mix 4 parts R1 with 1 part R2.
The manufacturer states approximately 2 weeks at 2–8°C, protected from direct light.
CK-MB is a cardiac-associated creatine kinase isoenzyme historically used in the laboratory evaluation of myocardial injury. Current interpretation should follow contemporary clinical practice and should not rely on CK-MB alone.
No. It is intended for professional in vitro diagnostic use only.
The laboratory should verify analyser compatibility, wavelength, kinetic programming, reaction temperature and validated method before ordering.
The product can be ordered from Microsidd India through microsidd.com, subject to stock availability.
Yes. Microsidd supplies diagnostic and laboratory products to serviceable locations across India.
The information on this product page is provided for general product identification, procurement and educational purposes only.
This product is intended for professional in vitro diagnostic use by trained laboratory personnel.
CK-MB is a laboratory biomarker and should not be used alone to diagnose or exclude myocardial infarction or other cardiac conditions. Current clinical evaluation of suspected myocardial injury may require cardiac troponins, ECG findings, symptoms and other clinical investigations.
The information provided by Microsidd India does not replace the official Swemed Diagnostics package insert, analyser instructions, laboratory standard operating procedures, calibration requirements, quality-control procedures or professional medical judgement.
Specimen requirements, methodology, reagent preparation, analyser settings, reference intervals, storage, stability, quality-control requirements and interpretation must always follow the current manufacturer instructions and validated laboratory procedures.
This product is non-returnable and non-exchangeable.
Please verify the brand, model, compatibility, pack size and product specifications before placing your order.
For laboratory reagents, customers should specifically verify the test parameter, methodology, analyser compatibility, reagent configuration and pack size before ordering.
Genuine cases involving an incorrect product received will be handled separately according to Microsidd.com's applicable policies and applicable law.
An original, continuous, unedited and uncut unboxing video is compulsory for making any claim regarding an incorrect product received.
| Specification name | Specification Value |
|---|---|
| Chemical grade | Reagent, Laboratory |
| Color pattern | White |
| Test method | Lab analysis |
| Test sample | Blood |
