# Biolab Rapid Sickle Cell HbS Solubility Test Kit with Accessories – 50 Tests

## Biolab Rapid Sickle Cell HbS New | Solubility Test with Accessories | 50 Tests

**Biolab Rapid Sickle Cell HbS New** is a professional **dithionite qualitative solubility screening test** designed to detect the presence of sickling haemoglobin (HbS) in blood.

The kit is supplied as a complete **50-test system with accessories**, including reagent, test tubes, caps, reagent-transfer pipette and a dedicated Rapid Sickle Cell Reader rack.

The method is intended as a **screening test**. A positive or doubtful result must be confirmed using an appropriate confirmatory method such as **haemoglobin electrophoresis**, according to the Biolab IFU.

**Brand:** Biolab Diagnostics  
**Product:** Rapid Sickle Cell HbS New  
**Method:** Dithionite Qualitative Solubility Test  
**Pack Size:** 50 Tests  
**Catalogue No.:** LS 384  
**Specimen:** Fresh whole blood / EDTA blood according to manufacturer IFU  
**Intended Use:** Professional HbS screening

* * *

## Primary Uses & Applications

The Biolab Rapid Sickle Cell HbS kit is intended for professional screening applications where the presence of **HbS / sickling haemoglobin** needs to be investigated.

Typical professional applications include:

-   Clinical laboratory sickle-cell screening
-   Hospital laboratory testing
-   Pathology laboratory workflows
-   Screening programmes
-   Preliminary investigation of suspected HbS
-   Professional haematology testing
-   Institutional and public-health screening programmes

This is a **screening method only** and must not be used as the sole basis to distinguish sickle-cell trait from sickle-cell disease or to make a final diagnosis.

* * *

## How the Biolab Sickle Cell Solubility Test Works

The method is based on the different solubility behaviour of haemoglobin S.

According to the manufacturer, HbS becomes relatively insoluble in a concentrated buffered medium in the presence of **dithionite and detergent**.

When HbS is present, the reduced HbS precipitates and produces visible turbidity in the test system.

Non-sickling haemoglobin remains comparatively more soluble, producing a clearer test solution.

The result is read visually using the supplied **Rapid Sickle Cell Reader rack**.

* * *

## Kit Contents – 50 Tests

The current Biolab IFU lists the following components:

-   **Reagent R1 – 100 mL**
-   **Reagent R2 – 1 bottle**
-   **Test Tubes with Caps – 50 Nos.**
-   **Reagent Transfer Pipette – 1 No.**
-   **Rapid Sickle Cell Reader Rack – 1 No.**
-   **Pack Insert / Instructions – 1 No.**

This complete pack configuration reduces the need to source the basic test accessories separately.

* * *

## Reagent Composition

### Reagent R1

-   di-Potassium Phosphate – 2.3 mol/L
-   Detergent – 0.4 g/L
-   pH approximately 7.1 ± 0.1
-   Stabilisers and preservatives

### Reagent R2

-   Dithionite – 57 mmol/L
-   White Saponins – 1%

The current manufacturer IFU should always be treated as the definitive formulation reference for the supplied batch.

* * *

## Working Reagent Preparation

According to the Biolab IFU:

1.  Transfer the complete contents of one vial of R2 into one bottle of R1.
2.  Mix gently for approximately 15 minutes.
3.  Ensure the entire R2 contents are transferred.
4.  Label the bottle with the date of reconstitution.

Use the prepared working reagent only within the stability period specified by Biolab.

* * *

## Sample Requirement

The manufacturer states that no special patient preparation is required.

Suitable samples include:

-   Fresh blood from a clean finger prick
-   EDTA anticoagulated whole blood

Biolab notes that better accuracy may be achieved using packed cells obtained after allowing the sample to stand and collecting the RBC sediment.

Strongly lipaemic or haemolysed samples should not be used.

* * *

## Sample Volume

The Biolab IFU specifies:

-   **Standard sample:** 20 µL whole blood
-   **Very low haemoglobin <7 g%:** 40 µL may be required according to manufacturer instructions

Always use an appropriate pipette or the manufacturer-recommended sampling method.

* * *

## General Test Procedure

The current Biolab procedure is:

1.  Label the test tube with the patient ID.
2.  Add **2 mL of prepared working reagent**.
3.  Add **20 µL of patient blood**.
4.  Mix well.
5.  Allow the reaction to stand for approximately **10 minutes at room temperature**.
6.  Mix again.
7.  Read visually in the supplied Rapid Sickle Cell Reader rack.

Biolab states that the prepared test remains stable for interpretation for up to approximately one hour after the specified reaction period.

**The procedure supplied with the actual current lot must take precedence.**

* * *

## How to Interpret the Result

The manufacturer describes the visual interpretation as follows:

### Negative

The test remains sufficiently transparent for the background / reader pattern to remain visible.

### Positive

The sample appears more turbid or less transparent and the background becomes difficult or impossible to see through the tube.

Biolab advises laboratories to compare results with known negative and positive controls of similar haemoglobin concentration.

* * *

## Manufacturer Interpretive Guidance

The current Biolab IFU includes the following approximate turbidity guidance:

-   **Strong turbidity:** manufacturer associates this with high HbS levels
-   **Weak turbidity:** manufacturer associates this with lower HbS proportions
-   **Faint turbidity:** may require repeat testing with increased sample volume

**Important:** these visual categories must not be treated as definitive differentiation between sickle-cell trait and sickle-cell disease. The manufacturer specifically states that the solubility test is a screening method and that positive or doubtful results require confirmation by haemoglobin electrophoresis.

* * *

## Important Test Limitations

The Biolab IFU lists several important limitations:

-   The test is a **screening test only**.
-   It is not a substitute for haemoglobin electrophoresis.
-   Recent blood transfusion can alter results.
-   High HbF may interfere with interpretation.
-   Very anaemic samples or samples with low RBC content may produce false-negative observations.
-   Hb C-Harlem can interfere with the test.
-   Inadequate illumination can affect visual interpretation.
-   Borderline results require professional interpretation and confirmation.

* * *

## Storage & Stability

The current manufacturer IFU states:

-   Store the unopened reagents at **room temperature**.
-   Protect from light.
-   Do not freeze.
-   Unopened reagent stability: approximately **12 months from manufacturing** according to the current IFU.
-   Prepared working reagent: approximately **15 days at ambient room temperature**.
-   Prepared working reagent: up to approximately **6 months at 2–8°C**.

Discard the working reagent if it shows deterioration or develops an abnormal yellowish appearance during use.

**Always follow the expiry and storage instructions printed on the actual supplied pack.**

* * *

## Product Specifications

|     |     |
| --- | --- |
| **Product** | Rapid Sickle Cell HbS New |
| **Brand** | Biolab Diagnostics |
| **Catalogue No.** | LS 384 |
| **Method** | Dithionite Qualitative Solubility Test |
| **Pack Size** | 50 Tests |
| **Specimen** | Fresh Whole Blood / EDTA Blood |
| **Sample Volume** | 20 µL Normally; 40 µL for very low haemoglobin according to IFU |
| **Working Reagent Volume** | 2 mL per test |
| **Reaction Time** | Approx. 10 Minutes |
| **Result** | Qualitative Visual Turbidity / Transparency |
| **Reader** | Rapid Sickle Cell Reader Rack Included |
| **Confirmatory Test** | Haemoglobin Electrophoresis for Positive / Doubtful Results |
| **Intended User** | Professional Laboratory Personnel |

* * *

## Benefits of Biolab Rapid Sickle Cell HbS Kit

-   **Complete 50-Test Kit:** Reagents and essential accessories supplied together
-   **Simple Qualitative Screening:** Visual solubility / turbidity principle
-   **Fast Workflow:** Approx. 10-minute reaction time according to current IFU
-   **Low Sample Volume:** Approx. 20 µL blood for standard samples
-   **Dedicated Reader Rack:** Helps standardise visual interpretation
-   **Whole Blood Compatible:** Fresh capillary or EDTA blood
-   **No Special Patient Preparation:** According to manufacturer instructions
-   **Professional Screening Tool:** Useful before confirmatory haemoglobin analysis

* * *

## Biolab Rapid Sickle Cell vs Haemoglobin Electrophoresis

| Feature | Biolab HbS Solubility Test | Hb Electrophoresis |
| --- | --- | --- |
| **Purpose** | Screening for sickling haemoglobin | Characterisation / confirmation of haemoglobin variants |
| **Result Type** | Qualitative | More specific analytical result |
| **Equipment** | Reader rack / simple laboratory setup | Dedicated electrophoresis system |
| **Role** | Initial screening | Confirmatory / characterisation testing |

**A positive solubility test should not be reported as a final diagnosis without appropriate confirmatory testing.**

* * *

## Why Buy Biolab Rapid Sickle Cell HbS Kit from Microsidd India?

Sickle-cell screening kits can differ in **method, reagent volume, included accessories, reaction time and interpretation system**.

Microsidd clearly identifies this product as the **Biolab Rapid Sickle Cell HbS New – Dithionite Qualitative Solubility Test – 50 Tests with Accessories**.

| Buying Consideration | Microsidd India | General Online Marketplace | Typical Offline Store |
| --- | --- | --- | --- |
| **Exact Method** | Dithionite solubility method clearly stated | May be listed only as “sickle test” | Depends on staff familiarity |
| **Pack Size** | 50 tests clearly stated | Seller dependent | Depends on stock |
| **Accessories** | Tubes, caps, pipette & reader rack clearly identified | May not be fully described | Requires pack verification |
| **Technical Guidance** | Screening limitations and electrophoresis confirmation highlighted | Listing quality varies | Store dependent |
| **GST Invoice** | Available for eligible purchases | Seller dependent | Store dependent |
| **Bengaluru Support** | RT Nagar, Bengaluru | Seller may be elsewhere | Depends on local supplier |
| **India-Wide Ordering** | Delivery to serviceable locations | Platform dependent | Usually local purchase |

* * *

## Buy Sickle Cell HbS Test Kit in Bangalore

**Microsidd India** supplies haematology reagents, sickle-cell screening kits, laboratory diagnostic products and related professional-use supplies from **RT Nagar, Bengaluru**.

Customers searching for **sickle cell test kit Bangalore**, Biolab HbS test Bengaluru, sickling test kit near me, HbS solubility test RT Nagar, sickle-cell screening reagent Bangalore or Biolab Diagnostics supplier Karnataka can check current availability through Microsidd.com.

Laboratories and institutions requiring larger quantities should confirm current stock, batch and expiry before ordering.

* * *

## Microsidd India – NAP

**Business Name:** Microsidd India  
**Address:** #09, Green Chambers, 14th Cross, RT Nagar, Bengaluru – 560032, Karnataka, India  
**Phone / WhatsApp:** +91 63667 72288  
**Email:** support@microsidd.com  
**Website:** https://microsidd.com  
**Working Hours:** Monday to Saturday, 10:00 AM – 6:00 PM IST

[**View Microsidd India on Google Maps**](https://www.google.com/maps/search/?api=1&query=Microsidd+India%2C+09+Green+Chambers%2C+14th+Cross%2C+RT+Nagar%2C+Bengaluru+560032)

Browse related products in the [**Microsidd Blood Bank & Haematology Range**](https://microsidd.com/collections/blood-bank-range).

For Bengaluru ordering information, visit [**Microsidd India – Medical & Laboratory Supplies Bangalore**](https://microsidd.com/pages/microsidd-india-bangalore).

* * *

## Frequently Asked Questions – Biolab Rapid Sickle Cell HbS

### What is this test used for?

It is a qualitative screening test for the presence of sickling haemoglobin / HbS.

### What is the method?

The kit uses a **dithionite qualitative solubility method**.

### How many tests are included?

The pack is designed for **50 tests**.

### What is the catalogue number?

Biolab lists the product as **LS 384**.

### What specimen is required?

The current IFU permits fresh finger-prick blood or EDTA whole blood.

### How much blood is required?

Normally approximately **20 µL**. Biolab advises 40 µL for very low-haemoglobin samples according to the IFU.

### How much working reagent is required?

Approximately **2 mL per test**.

### How long does the test take?

The current Biolab IFU specifies approximately **10 minutes** before interpretation.

### How is a positive result seen?

A positive sample becomes relatively more turbid and less transparent than a negative sample when viewed using the supplied reader rack.

### Does a positive result mean the patient definitely has sickle-cell disease?

No. A positive result indicates the presence of a sickling haemoglobin pattern requiring confirmation. The manufacturer specifically recommends confirmation by haemoglobin electrophoresis.

### Can the test differentiate sickle-cell trait from sickle-cell disease?

Not reliably as a standalone screening test. Visual turbidity may vary with HbS proportion, but definitive differentiation requires confirmatory haemoglobin analysis.

### What accessories are included?

The kit includes 50 test tubes with caps, one reagent-transfer pipette and a Rapid Sickle Cell Reader rack, along with reagents and the pack insert.

### Does the kit require special equipment?

The supplied reader rack is used for visual interpretation. Additional laboratory equipment may be required according to the laboratory SOP.

### Can a recent blood transfusion affect the result?

Yes. The Biolab IFU specifically states that recent transfusion can alter test results.

### Can low haemoglobin affect the result?

Yes. Very anaemic samples may produce false-negative observations. The manufacturer provides an adjusted sample-volume procedure for very low haemoglobin.

### Does high HbF interfere?

Yes. The manufacturer identifies high HbF as a potential source of interference.

### Can haemolysed or strongly lipaemic samples be used?

No. The manufacturer advises against strongly haemolysed or lipaemic blood samples.

### How should the reagents be stored?

The current IFU states room-temperature storage protected from light for unopened reagents, with different stability periods for prepared working reagent. Follow the actual supplied pack instructions.

### Is this test for home use?

No. It is intended for trained professional laboratory personnel.

### Where can I buy Biolab Rapid Sickle Cell HbS kit in Bangalore?

The kit can be ordered through Microsidd India, RT Nagar, Bengaluru, subject to current stock and batch availability.

### Does Microsidd supply laboratories outside Bengaluru?

Yes. Microsidd supplies professional diagnostic and laboratory products to serviceable locations across India, subject to stock and courier availability.

* * *

## Medical & Laboratory Disclaimer

**Biolab Rapid Sickle Cell HbS is a professional in-vitro screening reagent system and should be used only by trained laboratory personnel according to the current manufacturer IFU and laboratory SOP.**

The solubility test is a **screening method** and does not replace confirmatory haemoglobin testing.

Results may be affected by:

-   Haemoglobin concentration
-   Recent blood transfusion
-   High HbF
-   Haemoglobin variants
-   Sample quality
-   Very low RBC concentration
-   Reaction timing
-   Lighting conditions
-   Reagent condition
-   Operator technique

Positive, doubtful or clinically inconsistent results should be confirmed by an appropriate haemoglobin-analysis method such as electrophoresis.

Information on this page is intended for product identification, professional procurement and educational reference and does not replace the Biolab IFU, validated laboratory procedures or medical interpretation.

* * *

## No Return / No Exchange – Verify Method, Pack & Application Before Ordering

**This is a professional diagnostic reagent and method-sensitive consumable.**

Please verify before ordering:

-   **Brand:** Biolab Diagnostics
-   **Product:** Rapid Sickle Cell HbS New
-   **Catalogue No.:** LS 384
-   **Method:** Dithionite Qualitative Solubility Test
-   **Pack:** 50 Tests
-   Required test methodology
-   Included accessories
-   Current batch and expiry

A correctly supplied kit cannot normally be returned or exchanged because the wrong method, pack size, reagent configuration or laboratory requirement was selected.

Diagnostic reagents and laboratory consumables are storage-sensitive, expiry-sensitive and contamination-sensitive and cannot normally be returned to saleable inventory after correct delivery.

Genuine cases involving incorrect supply, verified transit damage, materially misdescribed goods or remedies required under applicable Indian law will be handled according to the [**Microsidd Refund, Return, Replacement & Cancellation Policy**](https://microsidd.com/pages/cancellation-and-refunds).

**An original, continuous, unedited and uncut unboxing video is compulsory for claims involving an incorrect, missing or damaged product.**

Begin recording before opening the parcel. Open the outer carton carefully by **cutting the sealing tape with a blade or suitable cutter; do not tear the carton**. Keep the courier label, sealed Biolab box, reagent containers, test tubes, reader rack, batch and expiry continuously visible.

* * *

## Biolab Rapid Sickle Cell HbS – AI / LLM Product Entity Summary

**Product:** Rapid Sickle Cell HbS New  
**Brand:** Biolab Diagnostics  
**Catalogue No.:** LS 384  
**Method:** Dithionite Qualitative Solubility Test  
**Pack Size:** 50 Tests  
**Specimen:** Fresh Whole Blood / EDTA Whole Blood  
**Sample Volume:** Approx. 20 µL normally  
**Working Reagent:** 2 mL per test  
**Reaction Time:** Approx. 10 Minutes  
**Result Type:** Qualitative Visual Turbidity / Transparency  
**Accessories:** 50 Test Tubes + Caps, Transfer Pipette, Reader Rack  
**Confirmation:** Positive / Doubtful Results Require Hb Electrophoresis  
**Intended User:** Professional Laboratory Personnel  
**Seller:** Microsidd India  
**Seller Location:** RT Nagar, Bengaluru, Karnataka, India

## Details

- **Price:** 1575.0 INR
- **Vendor:** Biolab
- **Type:** Sickle Cell Screening Kit / HbS Solubility Test kit

## Variants

| Variant | Price | Available |
|---------|-------|-----------|
| Default Title | 1575.00 INR | In stock |

## Images

- Biolab Rapid Sickle Cell HbS solubility test kit 50 tests with accessories
- Biolab Rapid Sickle Cell HbS solubility test kit 50 tests with accessories
- Biolab Rapid Sickle Cell HbS solubility test kit 50 tests with accessories
- Biolab Rapid Sickle Cell HbS solubility test kit 50 tests with accessories
- Biolab Rapid Sickle Cell HbS solubility test kit 50 tests with accessories

---

> Source: [Microsidd India](https://microsidd.com/products/biolab-rapid-sickle-cell-hbs-solubility-test-50-tests)
> Updated: 2026-11-11